A serious health problem or trendy diet fad?
It seems that every second person you meet these days claims to be gluten intolerant. Is this just another diet fad that will come and go like so many before, or is this a real health problem that we should be taking seriously? Recent genetic-based research highlights that gluten intolerance is a real condition and if you are gluten intolerant, don’t know that you are and continue to have gluten, the health consequences are diverse and serious. This is why Gluten Intolerance DNA testing is so important.
Gluten intolerance is a genetic trait
There are a number of key genes that determine if you are gluten intolerant. People who have even a single mutation in any of these genes are absolutely gluten intolerant, will be for their whole life, and will always need to adopt a gluten-free diet. The mutation results in gluten being presented to their immune system as a risk factor and a threat, leading to inflammation, tissue destruction, an abnormal immune response and production of autoimmune antibodies.
A person with these mutations can have a 300% higher immune response to just a single gluten peptide molecule.
99% of people who are gluten intolerant don’t know it!
It is a common misconception that if you are gluten intolerant you will have gastrointestinal symptoms. Only 28% of people who are gluten intolerant have gastrointestinal symptoms such as bloating, pain, constipation or diarrhea. The main symptoms are actually foggy brain, fatigue, skin rashes, headaches and migraines, joint or muscle pain, depression, leg or arm numbness and anemia (low iron).
Researchers are strongly advocating that we should implement genetic screening for gluten intolerance mutations in newborns, before the introduction of cereals, to avoid the serious health consequences of this mutation.
Serious Health Consequences
The consequences of having gluten intolerance mutations are far more serious than some gastrointestinal discomfort. The genes that determine if you are gluten intolerant are a very important part of the immune system referred to as the Human Leukocyte Antigen (HLA) system, which is responsible for watching out for antigens, invaders, anything that is foreign to the body. Mutations in HLA genes, including gluten intolerance mutations, are a major cause of autoimmune disease. For people with gluten intolerance mutations, every time they eat gluten they are increasing their risk of developing a wide range of autoimmune diseases. Even if these people stop eating gluten they still have a considerable autoimmune risk. Anyone who is gluten intolerant has to manage this risk carefully.
Gluten intolerant mutations increase the risk of a wide range of diseases
- Can increase the risk of developing celiacs disease by 600%
- Type 1 Diabetes
- Type 2 Diabetes
- Autoimmune Thyroid (Hashimoto’s/Graves)
- Autoimmune Liver Disease
- Autoimmune Kidney Disease
- Multiple Sclerosis
- Gut Dysbiosis
If you have a 23andMe or an AncestryDNA genetic profile you already have this genetic information in your raw data file. We can take your raw file and analyze your data for you – upload your file here.